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Dry Mouth at Night, Too Dry to Sleep? Imperial Physician Gong Tingxian's Blood-Nourishing, Yin-Nourishing Treatment for Sjögren's Syndrome (Siwu Tang + Liuwei Dihuang Wan)
Search keywords: Dry mouth at midnightDry mouth at nightParched mouth and tongueCan't sleepAwake in the middle of the nightIrritable and thirsty
Condition (medical term): Sjögren's syndrome, Yin deficiency with internal heat, Blood deficiency

📋 Case Details

Erac. 1580s–1610s (Ming dynasty, Gong Tingxian 1538–1635)SourceMedical cases of Doctor Gong Tingxian, explained by Doctor Luo Dalun · Classical case (Ming dynasty)DoctorDoctor Gong Tingxian (龚廷贤)PatientThe wife of Magistrate Guan (an official's lady of the Ming dynasty, with a hot temper, stagnant liver qi, blood deficiency and yin deficiency)NarratorDoctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine)
ConditionSjögren's syndromeYin deficiency with internal heatBlood deficiencyStagnant liver qi with heatDry eyes and dry mouth syndromeDeficiency fire blazing upwardUpper excess with lower deficiencyDepletion of body fluids
SymptomsDry mouthInsomniaRestlessnessChest tightnessLoss of appetiteRed tongueDry mouth at midnightDry mouth at nightParched mouth and tongueCan't sleepAwake in the middle of the nightIrritable and thirstySpitting thick sticky phlegmSticky phlegmTight chest and noisy, uncomfortable stomachNo appetiteNot wanting to eat
MedicineSiwu Tang (Four Substances Decoction), reinforced with sheng di huang (raw rehmannia), mai dong (ophiopogon), tian hua fen (trichosanthes root) and xuan shen (figwort root) to nourish yin; huang lian (coptis), zhi mu (anemarrhena) and zhi zi (gardenia) to clear heat; jie geng (platycodon), zhi shi (bitter orange) and qing pi (green tangerine peel) to move qi; gan cao (licorice) to harmonizeLiuwei Dihuang Wan (Six Flavor Rehmannia Pill) plus sheng di huang, mai dong, zhi mu, xuan shen, tian hua fen, chuan bei mu (Sichuan fritillaria), wu wei zi (schisandra) and huang lian, made into honey pillsQiju Dihuang Wan (Wolfberry and Chrysanthemum Rehmannia Pill)Shu di huang (prepared rehmannia)Dang gui (Chinese angelica)Chuan xiong (ligusticum)Bai shao (white peony)Sheng di huang (raw rehmannia)Mai dong (ophiopogon)Tian hua fen (trichosanthes root)Xuan shen (figwort root)Huang lian (coptis)Zhi mu (anemarrhena)Zhi zi (gardenia)Jie geng (platycodon)Zhi shi (bitter orange)Qing pi (green tangerine peel)Chuan bei mu (Sichuan fritillaria)Wu wei zi (schisandra)Gan cao (licorice)Gou qi zi (wolfberry)Ju hua (chrysanthemum)Sha shen (glehnia root)
DoctorDoctor Gong Tingxian (龚廷贤)Narrated by Luo Dalun
SourceMedical cases of Doctor Gong Tingxian, explained by Doctor Luo Dalun

Dry Mouth at Night, Too Dry to Sleep? What an Imperial Physician Did About It

Patient search terms: dry mouth at midnight / dry mouth at night / parched mouth and tongue / can’t sleep / irritable and thirsty / spitting thick sticky phlegm

Medical terms for this condition: Sjögren’s syndrome · yin deficiency with internal heat · blood deficiency with qi stagnation · upper excess with lower deficiency

Opening: an official’s lady, too dry to sleep at night

Today’s case comes from Doctor Gong Tingxian, the imperial physician of the Ming dynasty. Doctor Luo Dalun holds him in the highest regard: he says he picks up Gong Tingxian’s books again and again, and whenever a case truly tests clinical skill, this old master’s moves are genuinely beautiful.

💬 Note from Doctor Luo: Why do I tell one case every day? I want everyone to understand, through stories, how Chinese medicine actually looks at illness — to take the doctor’s medical thinking apart piece by piece. Then, when the time comes to look after your own body, you have a framework in your head.

Today’s patient was the wife of Magistrate Guan — a lady from an official household. When Gong Tingxian later organized his case notes, he wrote four characters for her: qi stagnation generating fire (qi yu sheng huo). Four characters, and the whole story of this illness is told.

Who was she? The case notes say it in four characters: qi stagnation generating fire

Lay out this lady’s symptoms one by one, and quite a few of you are probably already nodding:

She couldn’t sleep once midnight came; her mouth was parched and she felt restless — how dry? As if her mouth were lined with sandpaper; run your tongue over it and it rasped. When it got really bad, she couldn’t even get her voice out; irritable and thirsty, restless inside, always wanting water; she spat thick sticky phlegm — so sticky that her throat never felt clear, and she had to get up and rinse her mouth with tea water to moisten it; her chest was tight and noisy — a stuffy, uncomfortable feeling; she ate little — no appetite, no desire for food.

💬 Note from Doctor Luo: This dry mouth is especially common at night. Many elderly people must get up in the middle of the night for a drink — one cup, then another — because if they don’t moisten their mouth, they simply cannot sleep properly. The tongue feeling like sandpaper — that description is not exaggerated at all. Quite a lot of people have this, especially older people.

Now look at the tongue: red tongue, thick black coating. The tongue is red — that means heat. The coating is black, thick and hard, like a layer of skin, a shell — the heat has built up to a high degree. First the coating turns yellow; when the heat grows fierce it turns black and thick, like a shell.

How far had the illness gone? One pulse reading: upper excess, lower deficiency — the trouble is below

When Gong Tingxian took her pulse, he saw the whole picture at once: both cun pulses were flooding and rapid — the cun position represents the heart and lungs, and both cun pulses flooding and racing meant the qi was surging upward; both chi pulses were empty — the chi position represents the kidneys, and pressing down he found emptiness, deep deficiency; the right qi-kou (the right cun) was also full. What is this? Upper excess with lower deficiency (shang sheng xia xu).

💬 Note from Doctor Luo: Upper excess with lower deficiency — the symptoms on top look as solid as a true excess, but the root is almost always deficiency below. The “dragon-fire blazing upward” (long lei zhi huo shang ben) we discussed before is exactly this pattern: the lower part is depleted, the legs are ice-cold, the fire cannot be held and rushes upward, and the upper body shows a full display of heat — sore throat, swollen throat, toothache, swollen parotid glands, trigeminal neuralgia, all of it. Why is the lower part depleted? Water fails to nourish wood: the kidney holds both yin and yang; when yin and yang cannot join, the lower part empties and the qi machine surges upward. So the root of upper excess with lower deficiency is usually deficiency below.

Combined with this lady’s situation, Gong Tingxian’s verdict was: blood deficiency, qi stagnation, and fire. Blood deficiency is bound up with the deficiency below; and the root of the whole illness is qi stagnation generating fire — this lady had a temper. After Gong Tingxian became famous, most of the patients who sought him out were wives and daughters of officials and wealthy merchants — and plenty of those women had hot tempers. He points this out again and again in his case notes.

Layer one of the prescription: Siwu Tang (Four Substances Decoction) — the thousand-year formula for nourishing blood

How did he treat it? Gong Tingxian wrote a prescription built on Siwu Tang. What is Siwu Tang? Shu di huang (prepared rehmannia), dang gui (Chinese angelica), chuan xiong (ligusticum) and bai shao (white peony) — four herbs, the ancestral formula of Chinese medicine for nourishing blood. Whenever you need to nourish blood, this is the first formula that comes to mind — a classic distilled from ancient experience.

💬 Note from Doctor Luo: Siwu Tang comes from the Song dynasty’s Taiping Huimin Heji Ju Fang (Formulary of the Imperial Pharmacy) — the same generation that gave us Huoxiang Zhengqi San and Sijunzi Tang. The Song dynasty gathered these famous formulas and spread them across the empire, and everyone since has benefited. Go to Taiwan today and you’ll find countless health products and foods built on Siwu Tang — granules, pastes, all of them nourishing women on a Siwu Tang base. Eat them for a while and the complexion turns rosy; it’s wonderful for regulating the body.

Layers two and three: nourish yin and moisten dryness + clear heat and move qi

Nourishing blood alone was not enough — this lady was dry to the bone. So on top of Siwu Tang, Gong Tingxian added yin-nourishing herbs:

  • Sheng di huang (raw rehmannia) — nourishes kidney yin;
  • Mai dong (ophiopogon) — nourishes lung yin;
  • Tian hua fen (trichosanthes root) — nourishes yin and moistens dryness;
  • Xuan shen (figwort root) — clears heat and nourishes yin, able to draw the kidney’s yin fluids upward to moisten the throat. For a parched, dry mouth, a little xuan shen works especially well.

💬 Note from Doctor Luo: These are the old master’s classic moves. On the foundation of nourishing blood, raise the yin of the lungs and kidneys; when the yin fluids are sufficient, the dryness above naturally eases.

Then he added heat-clearing herbs: huang lian (coptis), zhi mu (anemarrhena), zhi zi (gardenia) — she had liver fire, and the fire had to be cleared. Then qi-moving herbs: jie geng (platycodon), zhi shi (bitter orange), qing pi (green tangerine peel) — her illness came from qi stagnation; simply tonifying was not enough, the qi had to be untangled. Qing pi is the peel of unripe green oranges — its power to move and break up qi is very strong. Finally a little gan cao (licorice) to harmonize the whole formula.

Nourish blood as the lead, nourish yin as support, and cover clearing heat and moving qi as well — this is precisely the approach Doctor Zhu Danxi excelled at. Gong Tingxian deeply respected Zhu Danxi and studied his thinking all his life.

A few doses change the whole picture; then pills to finish the job

Several doses brought results — the effect was good, and the big picture changed. What now? Gong Tingxian gave her Liuwei Dihuang Wan (Six Flavor Rehmannia Pill), plus sheng di huang, mai dong, zhi mu, xuan shen and tian hua fen — all yin-nourishing; plus chuan bei mu (Sichuan fritillaria) to transform phlegm — especially good for this kind of dry phlegm; plus wu wei zi (schisandra) to astringe and gather the yin, holding the medicine’s power in; plus a little huang lian to tend the fire that was still there.

He ground these into powder, mixed them with honey into pills, and she took them batch after batch. When that batch was finished, the illness was completely gone — every symptom disappeared, she was fully well.

💬 Note from Doctor Luo: To be honest, I deeply suspect this lady relapsed. Why? This kind of illness is basically a personality problem. A constitution of liver fire and yin deficiency driven by temperament is long-term; the moment the temper flares, it can all come back. So this is an illness that needs long-term care and a change of mindset on the patient’s part. Old people can’t change their personalities — so they just take care of themselves slowly.

Doctor Luo’s personal case: my own mother is exactly this type

At this point, Doctor Luo Dalun told his own mother’s story — very vivid.

💬 Note from Doctor Luo: My mother is eighty-seven this year. Her whole life she has been quick-tempered, driven, and a worrier. Her tongue is bright red every single day — I look at it and I worry. She basically doesn’t take decoctions anymore; every day she just takes Qiju Dihuang Wan — Liuwei Dihuang Wan with gou qi zi (wolfberry) and ju hua (chrysanthemum) added. Why those two? Because my mother’s eyes are especially dry — the liver opens into the eyes, and when liver fire keeps burning, the eyes go dry.

How much does she worry? When I eat with her, she watches every single piece of food on the table: eat more of this one, just one bite of that one. The moment I reach for something, she asks at once: “What are you looking for? What are you looking for?” Sometimes I can’t help asking: “Mom, do you have radar? You know what everyone around you is doing, and you have to manage all of it?” — People with this temperament have liver fire blazing every single day; that fire burns inside the body, scorching the yin fluids, and finally they land in a state of yin deficiency.

💬 Note from Doctor Luo: So the moment I see a tongue I know whether the person is a worrier. Once I looked at an auntie’s tongue and said: “Auntie, you worry about everything, you’re a driven person.” Her family was stunned: “Oh my goodness, you can read fortunes! You hit it exactly!” — Not because I’m so skilled; it’s because my mother is the same. This is a life pattern: quick-tempered, driven, strong-willed, worrying elders — and many women too: worriers, heavy hearts, hot tempers — in the end their illnesses are all tied to liver fire.

Back to the case: this Lady Guan surely had a big temper too. Temper flares, fire burns; fire burns, and yin fluids and blood are slowly dried out — in the northeastern dialect, “dried up like a wok left on the stove.” When they’re dried out, the fire still rushes upward: hence the black tongue coating, no appetite, tight chest, restless nights, and the ritual of rinsing the mouth with tea water every night. Siwu Tang nourishes blood — the blood of the heart and liver, above all liver blood, so the liver fire stops burning; sheng di huang, mai dong, tian hua fen and xuan shen build the body fluids; huang lian and zhi zi clear fire; jie geng, zhi shi and qing pi move qi — every piece fits.

Why “nourishing yin” is so misunderstood: the truth about Zhu Danxi

Here Doctor Luo cleared up a widespread misunderstanding — about Zhu Danxi’s yin-nourishing approach.

💬 Note from Doctor Luo: Some people say Zhu Danxi only understood nourishing yin and ignored warming yang, and that he harmed countless patients. But look at this case: a person this dried out — would warming yang work? Doctor Wang Mengying’s books are full of such examples: patients with genuine heat patterns met doctors who could not tell cold from heat, threw in gan jiang (dried ginger) and fu zi (aconite) to warm yang, and the patient’s tongue dried up, then they couldn’t speak — some even died with a dried tongue. Wang Mengying spent his whole life rescuing such people; some he saved, some he couldn’t. Recently, for no clear reason, a fashion has arisen of “everyone must warm yang” — even during my livestreams people come and say: “You’re of the yin-nourishing school; I’m of the warming-yang school.” I say: what schools! Whatever patient you meet, treat with whatever method fits. Heat calls for cooling, cold calls for warming — Chinese medicine values balance and impartiality, guiding people back to equilibrium. There is no such thing as “warming yang alone is enough” or “clearing heat alone is enough.”

And one more crucial point: a large share of what Zhu Danxi called nourishing yin was actually nourishing blood. When he said “yin,” he included the fluids, blood and essence — the moistening liquid substances; blood, properly classified, also belongs to yin. That’s why Zhu Danxi used Siwu Tang so much — and he also commonly used Sijunzi Tang, ren shen (ginseng), bai zhu (atractylodes) and the qi-tonics. His yin-nourishing teaching became famous, but at its core it was nourishing blood.

💬 Note from Doctor Luo: Body fluids and blood share the same source — Chinese medicine says “blood and sweat share the same origin”: both are the body’s liquids, just used differently. So nourishing blood and nourishing yin can be done together, and when you replenish one you replenish the other — a wonderfully efficient idea. Fire burning here damages precisely the fluids and yin-blood, and this lady is the perfect example.

A word for modern readers: with Sjögren’s syndrome, first tell cold from heat

Under today’s disease names, many people with this lady’s condition are told they have Sjögren’s syndrome — dry eyes, dry mouth, tongue dry as sand at night.

💬 Note from Doctor Luo: Western medicine gives it a name, “Sjögren’s syndrome,” then it’s spray and moisten the throat every day — few methods address the root. But from the perspective of Chinese medicine, for a very large share of these people nourishing yin is enough — as long as the tongue is red, you can consider nourishing yin. For people with yin deficiency and blood deficiency, this approach is exactly right. Not a hundred percent, of course, but a great many cases are yin deficiency, and this direction deserves attention.

Look back at this case and you’ll find: an illness treated in the Ming dynasty maps perfectly onto today. Plenty of people right now are exactly like this — dry mouth at midnight, can’t sleep, restless, spitting sticky phlegm, low mood, quick temper… Understanding the treatment logic matters more than memorizing one formula.

Bonus: an approach for long-term care

Finally, Doctor Luo shares the long-term care approach:

💬 Note from Doctor Luo: For long-term care, you can take Liuwei Dihuang Wan; if the yin-nourishing power feels insufficient, decoct sheng di huang, sha shen, mai dong, zhi mu and xuan shen into a tea and use it to wash down the Liuwei Dihuang Wan; if there’s fire, add a tiny bit of huang lian — even one gram will do. What we’re learning is the framework — nourish blood and yin together, add something to move qi, add a little to clear fire: that framework is fairly complete.

At the end, Doctor Luo added a heartfelt remark: this is the post-pandemic era. People who have built up knowledge reserves in peacetime don’t panic when something comes up — a little adjustment and they’re fine. People who never listen to Chinese medicine and never prepare are left scrambling. Listening to one case story a day is the best reserve you can build.


Compiled from Doctor Luo Dalun’s explanations of the medical cases of Doctor Gong Tingxian (imperial physician of the Ming dynasty, c. 1580s–1610s).

The original case text is from Medical cases of Doctor Gong Tingxian, explained by Doctor Luo Dalun; the commentary is based on public lectures by Doctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine).

This article is a historical case study for learning purposes only and is not medical advice. Please consult a qualified doctor if you are unwell.