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Blood in Stool, Night Sweats, and Chills and Fever? Doctor Xue Lizhai's Morning Qi-Tonifying, Afternoon Blood-Nourishing Cure for a Scholar
Search keywords: Bloody stoolBlood in the bowel movementSweating during sleepNighttime sweatingAlternating chills and feverFeeling cold and feverish
Condition (medical term): Heart-spleen dual injury, Spleen failing to command blood, Qi-blood deficiency

📋 Case Details

Erac. 1500s–1550s (Ming dynasty; Xue Lizhai / Xue Ji, 1487–1559)SourceCase Records of Doctor Xue (《薛氏医案》) by Xue Ji (Ming dynasty), with commentary by Doctor Luo Dalun · Classical case (Ming dynasty)DoctorDoctor Xue Lizhai (薛立斋)PatientA Confucian scholar (diligent student who neglected his diet and overused his mind)NarratorDoctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine)
ConditionHeart-spleen dual injurySpleen failing to command bloodQi-blood deficiencyQi-deficiency feverOverthinkingMental overworkHeart-spleen deficiencyQi and blood insufficiencyWeak constitution
SymptomsBlood in the stoolNight sweatsChills and feverFloating large pulse in all six positionsChoppy heart and spleen pulseBloody stoolBlood in the bowel movementSweating during sleepNighttime sweatingAlternating chills and feverFeeling cold and feverishChronic worrier
MedicineBu Zhong Yi Qi Tang (Tonify the Middle and Augment Qi Decoction)Gui Pi Tang (Restore the Spleen Decoction)Huang qi (astragalus)Ren shen (ginseng)Bai zhu (atractylodes)Long yan rou (longan fruit)Suan zao ren (sour jujube seed)Dang gui (Chinese angelica)Mai men dong (ophiopogon)Wu wei zi (schisandra)
DoctorDoctor Xue Lizhai (薛立斋)Narrated by Luo Dalun
SourceCase Records of Doctor Xue (《薛氏医案》) by Xue Ji (Ming dynasty), with commentary by Doctor Luo Dalun

Blood in Stool, Night Sweats, and Chills and Fever?

Patient search terms: blood in the stool / bloody stool / sweating during sleep / night sweats / alternating chills and fever / feeling cold and feverish / chronic worrier, overthinker

Medical terms: heart-spleen dual injury · spleen failing to command blood · qi-blood deficiency · qi-deficiency fever

Opening: even a scholar can fall this ill

The patient in today’s case is someone Doctor Xue Lizhai described in two words — a scholar (ru zhe), a man of learning. Doctor Xue said something similar in other case records: “The suffering of the scholar is known only to the scholar.”

💬 Note from Doctor Luo: Think about it — is studying hard actually hard? Day after day of diligent reading, burning the midnight oil, chasing a place in the imperial examinations. That is not a light job. Sitting all day, using the mind without rest, the body is quietly drained day by day. Doctor Xue Lizhai left behind more than three thousand case records in his lifetime, and a very large share of them are scholars and officials. They all shared one trait — too much worry, too much thinking.

The root: he ate badly first, then the blood came

This scholar first suffered irregular eating — he did not take care of his diet, no proper meals, nothing nourishing. The result? Blood in the stool, and the color was sometimes bright red, sometimes dark.

💬 Note from Doctor Luo: Before we go any further, let me share an essential piece of medical common sense: if you pass blood from the bowel, go to the hospital and get it checked — find out exactly where the blood is coming from. Bright red blood is usually less worrying; it means the bleeding is close to the exit, often just hemorrhoids. But if the color is like jam, be alert — it could point to something more serious, such as rectal cancer. And if the blood is black, the bleeding is coming from farther up the tract — possibly stomach bleeding. Never take it lightly. Too many people tell themselves, “It’s just hemorrhoids, no big deal,” put it off, and end up missing something serious. So remember: blood in the stool means go to the hospital first. That is the rule.

Half a year later: blood or sweat, chills or fever

The illness was not treated properly and dragged on for half a year, growing ever more complicated — if not blood in the stool, then night sweats; if not chills, then fever. Waves of cold, waves of heat.

💬 Note from Doctor Luo: Look at this patient’s state: bleeding, night sweats, chills, fever. Sounds like an external infection, an inflammation, doesn’t it? Many doctors see alternating chills and fever and immediately think of a cold. Don’t jump to that conclusion — this patient’s chills and fever had nothing to do with an external pathogen. The root was that the inside of the body had become empty.

The previous doctors had given him “blood and sweat medicines” — herbs to regulate the blood, herbs to stop sweating. They did nothing at all. Only then was Doctor Xue Lizhai called in.

What Doctor Xue Lizhai saw: floating large pulses, choppy at heart and spleen

Doctor Xue Lizhai felt the pulse and said four words: “Six pulses, floating and large.” Then another: “The heart and spleen positions are choppy.”

💬 Note from Doctor Luo: Let me explain this pulse. Six positions floating and large — does that mean strong upright qi? Quite the opposite! A floating, large pulse is not strength; it is the body’s last struggle. The pulse-qi is drifting upward to the surface, which tells you the foundation inside is about to give way. And a choppy heart-and-spleen pulse — what does choppy mean? Qi and blood are scarce, the blood is moving poorly, like a river nearly dried up, barely flowing. Floating-large is deficiency; choppy is deficiency too. Put the two together and the conclusion is clear — overthinking has injured the heart and spleen.

When the spleen is weak, the blood can no longer be “held”

Why does overthinking injure the spleen, and why does an injured spleen cause blood in the stool? Doctor Xue Lizhai gave a wonderfully vivid metaphor.

💬 Note from Doctor Luo: Let me pass on Doctor Xue’s explanation. Take a rope with a sandbag tied to the end and swing it around — why does the sandbag travel in a circle? Because the rope in your hand is pulling on it. That is the containing, restraining force. The moment you let go, the force is lost and the sandbag flies off in a straight line. The sandbag is like the qi and blood — and especially the blood and body fluids — inside us. Why do they stay in their proper channels? Because there is qi holding them in place. When spleen qi turns deficient, the holding power fails, and the blood “flies out” — so one person gets blood in the stool, another has abnormally heavy periods, another vomits blood; all kinds of bleeding appear. And it is not only blood that escapes — fluids escape too: some people develop edema. Overthinking injures the spleen; an injured spleen means deficient qi; deficient qi means it can no longer restrain; and the blood runs outward. In Chinese medicine this is the spleen failing to command the blood (pi bu tong xue).

Why both bleeding and night sweats? — blood and sweat share the same source

So what about the night sweats? Doctor Xue Lizhai said: “Blood is sweat, and sweat is blood” — blood and sweat share the same source.

💬 Note from Doctor Luo: “Blood and sweat share the same source” is one of the most important theories in Chinese medicine. According to this view, the body’s fluids can turn into sweat or into blood — they come from the same reservoir, the body’s jin ye (fluids). That is why the ancients had a rule: when a person has lost a great deal of blood (severe hemorrhage, very heavy periods), you must not casually induce sweating — the body’s fluid supply is already low; sweat it out and the fluids are devastated, and upright qi collapses. Modern people often don’t understand: sweat is waste that you excrete, blood is precious — how can they share a source? The ancients had great wisdom here: they draw on the same pool of resources. The fluids are that pool; if one side spends heavily, the other side runs short. So when fluids are damaged, blood is diminished and sweat is diminished too. This patient bleeding and sweating at the same time is the fluid reserve being drained from both ends.

Why chills and fever? — qi-deficiency fever, not fire

Chills are easy to understand — when qi and blood are depleted, of course you feel cold. But why the fever? Many people, on feeling heat, think “fire.” Doctor Xue Lizhai said: It is not fire. The fire is already so weak it is nearly extinguished.

💬 Note from Doctor Luo: This is the principle taught by Doctor Li Dongyuan — when qi is deficient enough, fever appears. It is called qi-deficiency fever, and Doctor Li Dongyuan called it “yin fire” or “fire in appearance only.” It looks like heat, but it is really deficiency: yang qi is very weak, the rise and fall of qi movement has gone wrong, and a false fire bubbles up. In this situation, Bu Zhong Yi Qi Tang can bring the fever down — “sweet and warm herbs can eliminate great heat.” When a person’s qi is exhausted to the limit, it is tonifying the qi that pulls that false fire back under control. So Doctor Xue Lizhai concluded: this patient’s chills and fever were, at bottom, qi and blood both deficient — and tonifying the middle qi was the correct path to cure the illness.

The signature move: tonify qi and lift yang in the morning, nourish blood and yin in the afternoon

The direction set, Doctor Xue Lizhai prescribed two formulas — and the way to take them was extremely precise: divided by time of day.

  • Before noon (morning): take Bu Zhong Yi Qi Tang (Tonify the Middle and Augment Qi Decoction) to tonify the source of the spleen and lung. Morning is when yang qi rises; riding the moment when all things’ yang is ascending, you fill up the yang of the spleen and lung and lift it upward — raising the sunken qi. The blood runs downward and leaks out because the qi has sunk; lift the qi back up and the blood is held.
  • After noon (afternoon): take Gui Pi Tang (Restore the Spleen Decoction) plus mai men dong (ophiopogon) and wu wei zi (schisandra) to nourish the blood of the heart and spleen and astringe the scattered fluids. In the afternoon yang begins to withdraw and gather — that is the time to nourish yin and blood. Ophiopogon moistens and nourishes yin, replenishing fluids (this patient’s fluid deficiency was plain to see); schisandra is sour and astringent — the blood you just nourished must be held in, so it does not leak out again.

💬 Note from Doctor Luo: Do you see it? Here is Doctor Xue Lizhai’s second signature approach! We have talked before about his time-of-day medication method: Bu Zhong Yi Qi Wan in the morning to lift yang, sometimes a little Xiao Yao Wan at midday, and at night Jin Gui Shen Qi Wan for yang deficiency or Liu Wei Di Huang Wan for yin deficiency. Today’s case is another pair: in the morning, Bu Zhong Yi Qi Tang to lift the yang of spleen and lung; in the afternoon, Gui Pi Tang to nourish the yin-blood of heart and spleen. Bu Zhong Yi Qi paired with Gui Pi — another model of time-divided prescribing. What is the reasoning? In the morning yang rises, so you do the work of lifting yang; in the afternoon yang gathers, so you do the work of nourishing yin — prescribe in rhythm with the heavens, and you get twice the result with half the effort.

Gui Pi Tang: the formula for overthinking and heart-spleen injury

Here we must take a closer look at Gui Pi Tang — the main afternoon formula in this case, and one Doctor Luo Dalun himself prescribes often.

💬 Note from Doctor Luo: Gui Pi Tang — I have talked about this formula many times, and it deserves special attention. What is in it? The Si Jun Zi Tang (Four Gentlemen Decoction) base for tonifying qi — ren shen (ginseng), bai zhu (atractylodes), fu ling (poria), gan cao (licorice) — plus blood-nourishing herbs: long yan rou (longan fruit), suan zao ren (sour jujube seed), dang gui (Chinese angelica). Why does a blood-nourishing formula include qi-tonifying herbs? Tonify qi in order to generate blood — qi and blood generate each other; nourishing blood alone often gives poor results, but when you nourish blood on a foundation of tonified qi, the blood can actually be produced. What does Gui Pi Tang treat? Specifically overthinking injuring the spleen: excessive mental work exhausts the blood of the heart and spleen — blood deficient and qi deficient at the same time; the spleen is too weak to hold things, so all kinds of bleeding, heavy uterine bleeding, irregular periods, insomnia and forgetfulness show up. This formula is used constantly today — there are so many modern people who overthink, whose hearts and spleens are both injured, whose qi and blood are insufficient. Gui Pi Tang is a formula I prescribe all the time, because an astonishing number of modern people match this pattern.

Under two months, everything healed

How did Doctor Xue Lizhai’s treatment turn out? “In not quite two months, all the symptoms were cured” — the blood in the stool, the night sweats, the chills and fever — all gone.

💬 Note from Doctor Luo: The illness was cured, and Doctor Xue wrote nothing further — but let Doctor Luo add one sentence on his behalf: this man still had to change his way of life. The illness is gone, but if you go right back to burning the midnight oil, chasing examinations, thinking without rest — you will be back on the medicine. If he could adjust his sleep, let go a little — “there are three hundred and sixty trades, and every one of them can make a champion” — do something else, let his mind settle, then the body could truly recover. Medicine only gives the body a hand; if the root habits do not change, the illness will come back sooner or later.

Remember this approach: lift yang in the morning, nourish yin-blood in the afternoon

The takeaway from this case is a remarkably practical framework for daily care.

💬 Note from Doctor Luo: The core of this case is one sentence: in the morning, generate yang with Bu Zhong Yi Qi; in the afternoon, nourish yin-blood with Gui Pi Tang. When we tell Doctor Xue Lizhai’s stories going forward, we will meet many more applications of this time-divided method — we’ll share them one by one. And if you are the type who overthinks, turns problems over in your head all day, with heart and spleen both injured — qi and blood insufficient, unable to sleep, heart palpitations, various kinds of bleeding — you can refer to this approach: tonify yang in the morning, gather yin-blood in the afternoon. Of course, any actual medication must be guided by a qualified practitioner; pattern differentiation (bian zheng lun zhi) is the foundation.


Case adapted from the lectures of Doctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine) on the case records of Doctor Xue Lizhai, from Case Records of Doctor Xue (《薛氏医案》).

The original case text is from Case Records of Doctor Xue (《薛氏医案》) by Xue Ji (Ming dynasty), with commentary by Doctor Luo Dalun; the commentary is based on public lectures by Doctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine).

This article is a historical case study for learning purposes only and is not medical advice. Please consult a qualified doctor if you are unwell.