🌿 Chinese Medicine Case Archive
中文
Always Drowsy and Want to Sleep All Day, Plus Vomiting, Diarrhea and Cold Hands and Feet? — Song Dynasty Formula Master Doctor Xu Shuwei Diagnoses Shaoyin Disease and Treats It With Wuzhuyu Tang (Evodia Decoction)
Search keywords: Always tired during the dayCan't keep eyes openNo energyExcessive sleepinessLethargySweating at the slightest movement
Condition (medical term): Shaoyin disease, Shaoyin cold-transformation pattern, Kidney yang deficiency

📋 Case Details

Erac. 1100s–1150s (Northern–Southern Song transition, Xu Shuwei 1079–1154)SourceShang Han Jiu Shi Lun (《伤寒九十论》, Ninety Discussions on Cold Damage), case on Shaoyin disease, cured with Wuzhuyu Tang · Classical case (Northern–Southern Song transition)DoctorDoctor Xu Shuwei (许叔微)PatientName not recorded (several days of an externally contracted cold illness: spontaneous sweating, sore throat, vomiting and diarrhea; a previous doctor called it latent pathogen, Doctor Xu Shuwei identified Shaoyin disease)NarratorDoctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine)
ConditionShaoyin diseaseShaoyin cold-transformation patternKidney yang deficiencyYang deficiencyDeficiency of yang qiExternally contracted cold
SymptomsDrowsiness despite plenty of sleep (dan yu mei)Spontaneous sweatingSore throatVomiting and diarrheaCold hands and feetThin and faint pulseAlways tired during the dayCan't keep eyes openNo energyExcessive sleepinessLethargySweating at the slightest movementThroat painNausea and vomitingLoose stoolsCold extremitiesChilly all overPale urineCraving hot drinksRestlessnessNighttime agitationDry heaving with droolingPain on top of the head
MedicineWuzhuyu Tang (Evodia Decoction)Sini Tang (Four Rebels Decoction)Huanglian Ejiao Tang (Coptis and Donkey-Hide Gelatin Decoction)Wu zhu yu (evodia)Ren shen (ginseng)Sheng jiang (fresh ginger)Da zao (jujube dates)Fu zi (aconite)Gan jiang (dried ginger)Huang lian (coptis)E jiao (donkey-hide gelatin)
DoctorDoctor Xu Shuwei (许叔微)Narrated by Luo Dalun
SourceShang Han Jiu Shi Lun (《伤寒九十论》, Ninety Discussions on Cold Damage), case on Shaoyin disease, cured with Wuzhuyu Tang

Always Drowsy and Want to Sleep All Day, Plus Vomiting, Diarrhea and Cold Hands and Feet?

Do you know anyone like this? They sit down at work in the morning and they’re already fighting to stay awake — groggy, heavy-lidded, the mind still spinning but the eyes refusing to open. Or worse: hands and feet like ice, throwing up whatever they eat, and diarrhea on top of it.

💬 Note from Doctor Luo: If this is you, or someone close to you, listen carefully to today’s story. When your yang qi can’t rally itself — when you’re sleepy all day long — Chinese medicine has a special name for it: dan yu mei (但欲寐, “only wanting to sleep”). In most cases it points to kidney yang deficiency. Today we continue our series on the great Song dynasty formula master Doctor Xu Shuwei (许叔微), who treated his patients with the classical prescriptions of the Shang Han Lun (Treatise on Cold Damage).

The patient: several days of cold, with sweating, pain, vomiting and diarrhea

Someone caught a cold illness — an externally contracted disease — and it had been going on for a few days. Three symptoms stood out:

First, spontaneous sweating. He sweated on his own, even without moving. The sweating was rather heavy.

Second, a swollen, sore throat. His throat hurt badly.

Third, vomiting and diarrhea. Up came vomiting; down came loose stools.

💬 Note from Doctor Luo: This is why it’s worth studying the Shang Han Lun seriously. Zhang Zhongjing is called the Sage of Medicine because his heart was so compassionate — every formula, when to use it, what variations to make when the condition changes, he wrote it all down clearly. But this patient’s illness was genuinely hard to judge.

The previous doctor said “latent pathogen”: the evil qi hides first, then strikes when conditions ripen

A physician was called in, and he diagnosed fu qi (伏气) — a latent pathogen.

What is a latent pathogen? It’s a classical TCM concept: external evil qi enters the body, doesn’t cause illness right away, and hides in some dark corner inside. Then, when conditions are right — when your body has grown weak, or the climate shifts — it finally erupts into disease.

💬 Note from Doctor Luo: This idea is remarkable. The Nei Jing (Inner Canon) says, “Injured by cold in winter, one will surely suffer warm disease in spring” — the cold damages you in winter, the pathogen hides, and in spring the warm epidemic breaks out. That’s the earliest statement of the latent-pathogen theory. When the Warm Disease school later branched off from the Cold Damage tradition, latent pathogen became one of its crucial theoretical pillars. You can understand it even better today: herpes zoster virus, hepatitis virus, HIV, and COVID — many people are infected and feel nothing at the time. Someone can test negative seven times, yet once their zheng qi (upright qi) is depleted and the body weakened, the hidden virus “whoosh” — it erupts, sometimes months later. Isn’t that exactly fu qi?

Doctor Xu Shuwei takes the pulse: this case is suspicious — not latent pathogen, but Shaoyin disease

Doctor Xu Shuwei was a master; he knew the Shang Han Lun inside out. After his examination he said: this case is suspicious — it looks like latent pathogen, but it isn’t.

Where’s the evidence? Article 283 of the Shang Han Lun: “When the patient’s yin and yang pulses are both tight, yet there is sweating instead — this is collapse of yang (wang yang). It belongs to Shaoyin disease, and the pattern calls for sore throat, vomiting and diarrhea.” The pulse is tight, but the patient sweats — this is collapse of yang: yang qi has already scattered, and with yang too weak to govern the body’s fluids, sweat pours out. The article says it plainly: this belongs to Shaoyin disease, and it should show sore throat, vomiting and diarrhea — exactly the symptoms before us!

💬 Note from Doctor Luo: This is the payoff of memorizing the text. Old masters like Liu Duzhou insisted students memorize the Shang Han Lun so thoroughly that the moment a patient describes a symptom, the relevant article springs to mind. Doctor Xu Shuwei added another point: a latent pathogen’s pulse must be weak and faint — but this patient’s pulse was tight in all three positions. How could this be latent pathogen? The pulse and symptoms are the authority. Had the wrong medicine been given here, the consequences would have been unthinkable.

What is Shaoyin disease? One of the last stops on the six-channel journey

The Shang Han Lun describes the six channels (liu jing): Zhang Zhongjing used cold evil as his imagined enemy to explain the body’s six layers of defense against external invasion.

Taiyang — the evil is at the surface; the fight begins. Yangming — the evil moves deeper; the body mobilizes everything, fighting fiercely, with high fever. Shaoyang — upright qi is a little depleted; the evil pushes deeper; the body can sometimes fight, sometimes not. Taiyin — the body enters decline; the spleen and stomach turn cold and deficient; the grain storehouse fails; resistance can’t be organized. Shaoyin — the evil is deeper still; the body can organize even less resistance. Last is Jueyin — the pivot of life and death; either death or recovery.

Where is Shaoyin? It’s the foot-shaoyin kidney channel and hand-shaoyin heart channel, with the focus on the kidney. The kidney dwells in the lower body and stores the source substance of life — it is the root of life itself. When external evil survives the earlier stages — the sweating, the purging — and keeps drilling inward until it reaches the kidney, the pathogen has struck at the very foundation.

💬 Note from Doctor Luo: There’s an old saying: “Cold damage tends to kill those whose lower body is already deficient” — in the same epidemic, some people come through fine and some die, and it’s the kidney-deficient who die. Look at COVID: young people were mostly fine; the ones we lost were mostly elderly, because in old age kidney qi declines day by day and overall disease resistance weakens. Some say Japanese society dared to open up because it’s an aging society and the government viewed the burden differently — think about it carefully: at bottom, it’s the same story of elderly kidney qi deficiency and failing resistance. And Shaoyin disease doesn’t only come from deep invasion of external evil — very often the patient’s own kidney qi was already insufficient. When you’ve been draining kidney qi, the kidney is weak, so the moment external evil arrives it goes straight for the kidney channel.

The two great markers of Shaoyin disease: a thin, faint pulse + dan yu mei

What are the principal pulse-and-symptom signs of Shaoyin disease? A thin, faint pulse, and dan yu mei (but wanting to sleep).

Why is the pulse both faint and thin? First, upright qi is insufficient: kidney qi is failing, the body lacks the strength to drive the blood vessels, so the pulse is faint. Second, qi and blood are both depleted: the blood is deficient too, the propelling force is weak, so the pulse is thin.

What does dan yu mei mean? Sleepiness all day long — yang qi simply cannot rally. In a healthy person, yang qi rallies in the daytime and the spirit is full; at night yang converges and hides, and that’s when one sleeps. But this kind of person is exhausted and drowsy in broad daylight — lying there, mind still muddled with unfinished thoughts, sometimes genuinely drifting into unconscious sleep. Why? Because their yang qi is insufficient, every body function is running low, and they have no capacity to move — all they can do is lie down.

💬 Note from Doctor Luo: Just the other day a friend asked me: why am I sleepy by mid-morning, groggy and dull? — That could very well be dan yu mei! Mornings are supposed to be when your whole body is full of drive; if you’re muddled instead, that’s a signal of kidney qi deficiency and failing yang. Remember these two: thin faint pulse, dan yu mei.

Shaoyin cold-transformation pattern: chilled all over, cold from the limbs to the heart and spleen

When external evil reaches Shaoyin, it can develop in two directions. First, the cold-transformation pattern (shaoyin hanhua zheng) — yang qi insufficient, cold evil deepening, yin cold growing stronger inside. What does it look like?

The whole body is cold; the four limbs are icy. Yang qi can’t drive the blood through the extremities, so the limbs turn cold. The classic formula is Sini Tang (四逆汤, Four Rebels Decoction) — fu zi (aconite) and gan jiang (dried ginger), the most classic yang-warming combination. I once told the story of a Li Dongyuan case: everyone read it as heat, Li Dongyuan read it as cold, and hurriedly decocted aconite medicine. The moment the decoction was ready, the child’s fingernails visibly turned blue — the interior was frozen through; the blood could no longer circulate!

Heart-kidney yang deficiency. The heart belongs to fire; the kidney holds both water and fire: kidney water rises to keep heart fire from flaming, heart fire descends to warm kidney water — this is called shui huo ji ji (水火既济), “water and fire mutually assisting.” They’re a pair. When the kidney is diseased, the heart is diseased too; the heart spirit is no longer roused, and dan yu mei arrives.

The spleen-earth loses its transport. Fire generates earth: when the ming men fire (life-gate fire) weakens, the spleen-earth is sure to fail — it can’t transport and transform, so upward there is vomiting, downward there is xiali qinggu (下利清谷): food comes out essentially undigested, not like food poisoning but with a faint smell and lots of water, and the appetite is terrible.

Lower burner deficiency-cold. The kidney governs water. When kidney yang is full, water is used where it should be used and excreted where it should be excreted. When kidney yang declines, the urine becomes copious and pale — pale urine is important: if the urine is yellow, that actually suggests heat inside. Then the patient craves hot drinks, the pulse is thin and faint, and he is always afraid of cold.

💬 Note from Doctor Luo: Hold this picture in your mind: icy limbs, constant sleepiness, vomiting, diarrhea, thin faint pulse, chills, pale urine — that’s the Shaoyin cold-transformation pattern, with both kidney yang and heart yang failing. Four characters sum it up: yang deficiency, cold dominance.

Shaoyin heat-transformation pattern: the other road, restless and sleepless

If external evil instead wounds kidney yin, it takes the other road — the heat-transformation pattern (shaoyin rehua zheng): yin deficiency with yang hyperactivity. The person is restless and cannot sleep — insomnia, dry mouth, dry throat, and a red tongue: deep red, with no coating or only an extremely thin one. In the cold-transformation pattern, by contrast, the tongue is pale, swollen, and scalloped at the edges.

For the heat-transformation pattern, what’s used? Huanglian Ejiao Tang (黄连阿胶汤, Coptis and Donkey-Hide Gelatin Decoction) with modifications. The later Warm Disease school’s treatment of heat evil wounding yin grew directly out of this.

💬 Note from Doctor Luo: Notice: in both cold and heat transformation, the throat hurts — because the kidney channel happens to run right up to the throat. Sore throat is just more common in the heat-transformation pattern. Today, though, we’re focusing on the cold-transformation pattern — the kind brought on by cold.

Doctor Xu Shuwei’s prescription: Wuzhuyu Tang, four herbs to warm a whole body of yang back

How did Doctor Xu Shuwei treat it? He gave Wuzhuyu Tang first, then added some nourishing and regulating remedies — and the patient recovered.

Wuzhuyu Tang (吴茱萸汤, Evodia Decoction) comes from the Shang Han Lun: wu zhu yu (evodia), ren shen (ginseng), sheng jiang (fresh ginger), and da zao (jujube dates). Ginseng supports upright qi; fresh ginger pairs with evodia to warm yang; jujube protects the spleen and stomach — the ginger and jujube together shield the digestive system, so the warming doesn’t go too far.

💬 Note from Doctor Luo: Evodia is a strikingly pungent, spicy herb. The ancients didn’t have chili peppers — chili only entered China after the Ming dynasty — so what made Sichuan food spicy in ancient times? Sichuan pepper — and evodia. Though mildly toxic, it was once used as a seasoning. It’s warming and targets the liver specifically: many later masters, including Doctor Zhang Xichun, used evodia to warm the liver whenever liver cold or injured liver yang appeared.

What does the text say? “In Shaoyin disease, with vomiting and diarrhea, cold hands and feet, and irritability to the point of feeling one wants to die — Wuzhuyu Tang governs.” This irritability is distinctive: with yang qi insufficient and yin qi dominant, the person is so agitated that hands and feet have nowhere to rest — fidgeting, stretching and flailing — and it’s usually worse at night: can’t sleep, body aching, restless and thrashing. Look at the tongue — if it’s pale, this is very likely Shaoyin disease, and Wuzhuyu Tang can restore it. Some people even develop psychiatric-like symptoms, shouting and crying at night — Wuzhuyu Tang works for that too.

💬 Note from Doctor Luo: Wuzhuyu Tang also treats Jueyin disease: dry heaving, spitting of drool, and pain at the very top of the head. Headache is divided by channel: forehead pain is Yangming, back-of-head pain is Taiyang, side pain is Shaoyang, and pain at the crown of the head belongs to the Jueyin liver channel — when the tongue is pale, there’s no sign of heat, and the whole body is cold, that’s Wuzhuyu Tang. It also treats cold-induced vomiting and retching. The beauty of this formula: evodia enters mainly the liver channel, but also the spleen, stomach and kidney channels. Whenever there’s vomiting, diarrhea, cold hands and feet — even top-of-head pain or that desperate irritability — consider it. The body is one whole: when kidney yang fails, everything turns cold, and the liver and stomach channels can’t escape it either. Wuzhuyu Tang warms its way straight through.

Doctor Luo’s closing notes: study the Shang Han Lun well and your clinical work will have direction

Today we’ve talked Shaoyin disease through. For those of you studying medicine professionally, go listen to the lectures of masters like Liu Duzhou, and work carefully through every detail of the Shang Han Lun — master it, and your clinical work becomes nearly miraculous.

💬 Note from Doctor Luo: When I was young, my treatments failed and patients walked around me — first, my pattern differentiation was wrong; second, I lacked method. Eventually I steeled myself and spent a full year seriously reading the Shang Han Lun. Immediately my clinical level rose: I knew what I was doing. Is it cold or heat? Where is the disease? What is its nature? How deep? How strong is the upright qi? — all clear. Zhang Zhongjing gave us the directional questions; every later physician built on those directions. The foundation of clinical medicine is right there.

For ordinary people, listening to these cases raises your understanding of the body a level: roughly knowing what state your body is in gives your self-care a direction. Tomorrow, we’ll talk about the concrete applications of Wuzhuyu Tang and more cases, so you can truly master this formula.

What to take away: daytime drowsiness that won’t lift, cold limbs, vomiting and diarrhea — especially with a thin faint pulse and pale urine — points to kidney yang deficiency and Shaoyin cold-transformation disease. Sore throat doesn’t always mean heat; the kidney channel runs to the throat, so a cold Shaoyin pattern can hurt it too. And don’t forget the pulse: latent pathogen and Shaoyin disease may look alike, but the pulse tells the truth.

Compiled from Doctor Luo Dalun’s commentary on Doctor Xu Shuwei’s case; the case comes from the Shang Han Jiu Shi Lun (《伤寒九十论》).

The original case text is from Shang Han Jiu Shi Lun (《伤寒九十论》, Ninety Discussions on Cold Damage), case on Shaoyin disease, cured with Wuzhuyu Tang; the commentary is based on public lectures by Doctor Luo Dalun (PhD in TCM diagnostics, Beijing University of Chinese Medicine).

This article is a historical case study for learning purposes only and is not medical advice. Please consult a qualified doctor if you are unwell.